Protective effect of Melatonin on clinical outcomes in patients with acute ischemic stroke

Phase 3

Recruiting

• Conditions: Acute ischemia stroke.; Cerebral ischemia; I67.82

• Registration Number: IRCT20231220060484N1
• Lead Sponsor: Islamic Azad University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Age:18 to 85 years old
Occurrence of stroke within the past 24 hours
NIHSS score of at least 4 and at most 27
Not eligible for thrombolytic therapy and thrombectomy

Exclusion Criteria

Pregnancy or breastfeeding
Acute or chronic intracranial hemorrhage or aneurism
Any type of cognitive or behavioral disorder
Concurrent inflammatory disease and/or malignancy
Patients with transient ischemic attacks
Sensitivity to Melatonin

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The severity of neurological function. Timepoint: Before the intervention and on the fifth day and one and three months after the intervention. Method of measurement: Using the National Institutes of Health Stroke (NIHSS) questionnaire and the modified Rankin Scale (mRS) questionnaire.