The Anterior Cutaneous Nerve Entrapment Syndrome (ACNES). Retrograde transforaminal paresthesia mapping (RTPM) for patients with ACNES. A pilot study for the anatomical distribution of neuropathic pain in the trunk at the level of the dorsal root ganglion.

Completed

• Conditions: 10009720; entrapped nerve abdominal wall; intercostal neuralgia; 10034606

• Registration Number: NL-OMON42590
• Lead Sponsor: Maxima Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-04-23

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

•Clinical diagnosis of ACNES:
•Localisation ACNES unilateral
•Clear, discrete pain point over the m. rectus abdominis
•Symptoms get worse upon flexing the abdominal muscles (Carnett*s sign positive)
•Good temporary effect of one local injection at the ACNES pain point with a local anesthetic. ;•Informed consent obtained and good apprehension of the procedure warranted
•Minimum age 18 years

Exclusion Criteria

•Pregnancy
•Allergy or hypersensitivity to lidocaine
•Prior treatment for ACNES, such as peripheral nerve blocks, Pulsed-Radio-Frequency, epidural injections, etc.
•Adequate follow-up not warranted, for example because of mental retardation, dementia or a language barrier
•Spinal surgical procedures at or between vertebral levels Th8-L2 in medical history
•Known coagulation disorders or use of anticoagulants

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The number of patients who confirm a one to one correlation between the<br /><br>clinical suspected anatomical dermatome in which their ACNES pain point is<br /><br>located and the corresponding dorsal root ganglion with RTPM</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Electrophysiological aspects:<br /><br>- If no one to one correlation is present, what is the mean number of DRG*s<br /><br>involved.<br /><br>- The relative contribution per DRG of elicited pain in the pain point in<br /><br>percentages.<br /><br>- Anatomical distribution of the elicited paresthesia using a drawing map<br /><br>- The mean mV to illicit a pain response.<br /><br><br /><br>Differentiation between peripheral and central sensitized pain:<br /><br>- The number of patients who report instantaneous complete remission of pain<br /><br>caused by a procedure after local anaesthesia in the targeted DRG*s.<br /><br><br /><br>Pain reduction:<br /><br>- Mean pain reduction on a Numeric Pain Rating Scale after PRF treatment<br /><br>compared to baseline directly after treatment and 2 weeks and 6 weeks after<br /><br>treatment.<br /><br>- The percentage of patients with a >30% and >50% pain reduction on a NPRS.</p><br>