Comparison of pre- and post cardiopulmonary bypass tranexamic acid effect on the amount of bleeding after coronary artery bypass graft surgery
- Conditions
- Amount of bleeding in Coronary Artery Bypass Graft Surgery.Other acute ischaemic heart diseases
- Registration Number
- IRCT2015090723933N1
- Lead Sponsor
- Tabriz University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
inclusion criteria: Patients under 75 years old candidate for cardiopulmunary Artery Bypass Graft surgery in the operation room of Tabriz Shahid Madani Hospital.
Exclusion criterua: Emergency surgery; Coagulopathy problems like Hemophilia, platelate below 100000 per ml, PT and PTT 1.5 times above normal range; Renal failure (Serum creatinine over 2mg/dl ); Allergy to Tranexamic acid;Existence of trombotic state (Subaracnoid Hemmorage, gallBladder disease,Vein thrombosis, Emboli); Plavix ( Clopidogrel) consumption during 7 days before operation; Streptokinase consumption during 48 hours before operation; Patients with poor heart contraction power (EF<35%); Aspirin consumption with high dose during 48 hours before operation; Repeated heart surgery operation (Redo);Active liver disease; Patients with Hb<10 g/dl
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of bleeding. Timepoint: During operation upto discharge. Method of measurement: Amount of bleeding from chest bottle per ml.
- Secondary Outcome Measures
Name Time Method