Acute Rehabilitation in Patients With COVID-19 Pneumonia

Not Applicable

Recruiting

• Conditions: COVID-19; Rehabilitation; Physical Medicine
• Interventions: Procedure: Acute rehabilitation program

• Registration Number: NCT05619666
• Lead Sponsor: Institut za Rehabilitaciju Sokobanjska Beograd

Brief Summary

COVID-19 can have different clinical manifestations including myalgia, arthralgia, neurological, cardiac, psychological and other manifestations.These patients are at greater risk of developing consequences of prolonged bed rest. Therefore physical medicine and rehabilitation could have an important role in the multidisciplinary treatment of these issues. Early respiratory and neuromuscular rehabilitation is necessary to improve functional physical limitations, performance, muscle strength, endurance as well as cognitive and emotional domains. Some studies proposed that rehabilitation protocols in the inpatient setting include early mobilisation, strength and endurance training with the aim of reducing weakness and dependency. This Study aimed to detect the effects of rehabilitation in patients with Covid-19 who were admitted in temporary Covid hospital in Serbia. Furthermore, to emphasize the importance of functional assessment of the patients, in identifying their problems and selections of priorities in planning the best therapeutic protocol.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-01
• Status Verified: 2022-11
• Study First Submitted: 2022-11-14
• Study First Submitted QC: 2022-11-15
• Last Update Submitted: 2022-11-15
• Study First Posted: 2022-11-17
• Last Update Posted: 2022-11-17
• Primary Completion: 2022-12
• Study Completion: 2023-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Positive pharyngeal or nasal swab for SARS CoV-2, 3) SP O2> 94% on admission, 4) body temperature under 37.5 5) Clinical stability defined by ability to perform bedside active mobilization without a reduction of oxygen saturation (SpO2) below 92%;

Exclusion Criteria

• 1. SP o2 < 94% on admission, 2) Moderate and severe heart failure (grade III and IV, NY heart Association), 3) Paresis or plegia as a result of CVI or neurodegenerative disease, 4) Impaired cognitive status.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Severity of COVID-19 infection	Acute rehabilitation program	Based on the severity of Covid-19 infection patients were divided into 2 groups: First group (MMG) mild to moderate group and second group (SSG) stable severe group.

Primary Outcome Measures

Name	Time	Method
functional outcome of cardiovascular and respiratory system	up to three weeks	six minute walk test (6MWT)
functional outcome of activity of daily living	up to three weeks	Bartel index (BI)
functional outcome of mobility	up to three weeks	"Time Up and Go" test (TUG)
functional outcome of static balance	up to three weeks	"One Leg Stance Test" (OLST)
functional outcome for assesing dyspnea	up to three weeks	Borg scale for dyspnea,
functional outcome of lower limbs strength	up to three weeks	"Sit To Stand" test (STS)

Trial Locations

Locations (2)

Institute for Rehabilitation; 🇷🇸 Belgrade, Serbia

Tamara Filipovic; 🇷🇸 Belgrade, Serbia