Measurement of the Cervix During Pregnancy According to Age of Conization
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 2
- Locations
- 1
- Primary Endpoint
- The main objective is to study the correlation between the size of the cervix and the age at conization. age at conization
Study Overview
Brief Summary
Treatment of precancerous lesions of the cervix by conization has been shown to increase the risk of premature delivery and premature rupture of the membranes. It has now been clearly established that the cervix is a growing organ during adolescence and early adulthood, It has been hypothetized that cervical conization during the growth phase reduced its growth potential, and induced shorter cervix during the upcoming pregnancy. No studies have been conducted investigating the age at which conization no longer had an impact on cervical size during pregnancy. This will help to identify the age at conisation below which patients will be identified as being at risk event, and thus offer increased monitoring and possibly prophylactic management by programmed strapping. We propose to measure the length of the cervix of pregnant patients who have benefited from conization, which is currently recommended by the Collège National des Gynécologues Obstetriciens Français .In addition, the investigators will use a control group consisting of non-con conical, parity-matched pregnant patients in whom a cervical measurement will also be performed.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patient referred since January 2008 with pregnancy between 2008 and 2017
- •Pregnancy after conisation
- •Cervix size between 21 and 24 SA before any obstetric event
- •Control group: parity matching, asymptomatic patients
Exclusion Criteria
- •Threat of late miscarriage,
- •Premature rupture of membranes before cervical echography,
- •Other pregnancies after study of 1st pregnancy after conisation,
- •No measurement of the conization specimen,
- •Lost to follow-up,
- •Twin Pregnancies
- •Patient under guardianship
Arms & Interventions
a group of women who have been conized
Previous conization
Intervention: Previous conization (Other)
control group with asymptomatic patients
on routine second trim no previous conization
Intervention: no previous conization (Other)
Outcomes
Primary Outcomes
The main objective is to study the correlation between the size of the cervix and the age at conization. age at conization
Time Frame: 1 day
Cervix length Measured during the second semester echography
Secondary Outcomes
No secondary outcomes reported