ocal antibiotic therapy in peri- implant inflammatio

Not Applicable

• Conditions: Periimplantitis.; Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified

• Registration Number: IRCT2013100114847N1
• Lead Sponsor: Vice Chancellor for research of Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1) Adults aged 18 or over with at least one implant in function for more than one year
2) Mild peri-imlant inflammatory diseases. defined as: presence of Bleeding on Probing, radio-graphic bon loss at the site of the implant less than 2 mm and probing depth more than 4 mm
Exclusion criteria:
1) Any related systemic diseases
2) Smoking
3) Pregnancy and lactation
4) Active periodontal disease
5) Consumption of systemic antibiotics in the late 3 months
6) Need for bacterial prophylaxis with systemic antibiotics
7) Long-term use of any drug affects periodontal tissue conditions
8) Probing depth greater than 6 mm at base line visit
9) Drug and alcohol abuse
10) Uncontrolled diabetes
11) Probing depth less than 4 mm at base line visit

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bleeding on probing (BOP). Timepoint: Baseline, 2 week and 3 month later. Method of measurement: Periodontal Probe.

Secondary Outcome Measures

Name	Time	Method
Peri implant probing depth. Timepoint: Baseline, after 2 weeks, after 3 month. Method of measurement: Periodontal prob.;Cytokines level in gingival crevicular fluid (GCF): IL-6, IL-17. Timepoint: Baseline, 2 week and 3 month later. Method of measurement: ELISA test.