Effect of Kanchanar Guggulu and Varunadi Kashaya with and without Virechana in the Management of Hypothyroidism in Adolescents
- Conditions
- Health Condition 1: E039- Hypothyroidism, unspecified
- Registration Number
- CTRI/2023/03/051020
- Lead Sponsor
- All India Institute of Ayurveda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Individuals of either gender between the age group of 10 - 16 years.
2.Diagnosed cases/new cases of hypothyroidism on the basis of Sr. TSH, T3, and T4 levels.
a.Subclinical hypothyroidism- 5-10µIU/ml with minimal or absence of symptoms
b.Clinical hypothyroidism- > 5 µIU/ml with clinical symptoms
3.Parents giving consent to participate in the study.
1.Recent thyroid surgery or radioiodine therapy within 1-year of the studyâ??s start date.
2.History or presence of clinically relevant cardiovascular, renal, metabolic, hematological, neurological, psychiatric, systemic, or infectious disease or malignant tumor, hereditary diseases, or syndromes.
3.Severe mental disorder.
4.Recent hospitalization for a major illness or elective surgery within 1-year of the studyâ??s start date
5.Diabetes mellitus type-1 patients.
6.Patient/Parents not willing to participate in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢To assess the efficacy in reducing the level of TSH.Timepoint: 0th day, 15th day, 60th day and 120th day
- Secondary Outcome Measures
Name Time Method â?¢To assess the efficacy in the improvement of clinical features of Hypothyroidism. <br/ ><br>â?¢To assess the efficacy in tapering the dose of levothyroxine. <br/ ><br>â?¢To assess the efficacy in Zulewskis clinical score. <br/ ><br>Timepoint: 0th day, 60th day and 120th day