Good combination therapy, alpha-blocker and imidafenacin, for Nocturia of Benign Prostatic Hyperplasia with OAB in Osaka-Hokuriku study group. - Good-Night study

Osaka-Hokuriku maleLUTS Conference Secretariat0 sites300 target enrollmentAugust 17, 2009

ConditionsOveractive Bladder

Overview

Phase: 未知
Intervention: Not specified
Conditions: Overactive Bladder
Sponsor: Osaka-Hokuriku maleLUTS Conference Secretariat
Enrollment: 300
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

Add-on anticholinaergic therapy for residual nocturia in patients with lower urinary tract symptoms receiving alpha 1- blocker treatmen: a multi-centre, prospective, randomised study. A short half-life anticholinergic is suggested to be safe and effective as an add-on therapy for residual nocturia in patients with male LUTS receiving alpha 1-blocker treatment. Anticholinergic admiistration nightly could reduce the nocturnal urine volume.

Registry

who.int

Start Date

August 17, 2009

End Date

July 1, 2011

Last Updated

2 years ago

Study Type

Interventional

Sex

Male

Investigators

Sponsor

Osaka-Hokuriku maleLUTS Conference Secretariat

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•1\) Urinary retention within a year 2\) Residual urine \>\=50mL 3\) Suspect of prostate cancer 4\) Treatment of any anti\-muscarinic agent or beta\-stimulants within a month. 5\) Indwelling catheter or self intermittent urinary catherization 6\) Diseases that affect nocturia (sleep apnea syndrome, Restless legs syndrome, insomnia etc.) 7\) The shift work and circadian rhythm disorder, patients with irregular lifestyle 8\) Bladder training conducted over the past 10 days 9\) Active urinary tract infection 10\) Having been given hormones or 5 alpha\-reductase inhibitor within the past six months 11\) Contraindication to Imidafenacin (Primary angle\-closure glaucoma, urinary retention, Obstructive intestinal disease, paralytic ileus, gastrointerstinal atony, myastania gravis) 12\) Judged as being unsuitable for the trial by the researcher.