ISRCTN68599804
Completed
未知
Safety and Effectiveness using DEXmedetomidine sedation versus propofol/alfentanil sedation during oesophagus interventions
Academic Medical Centre (AMC) (Netherlands)0 sites64 target enrollmentApril 16, 2013
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Academic Medical Centre (AMC) (Netherlands)
- Enrollment
- 64
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Eligible patients for participation in this clinical trial are those planned to undergo elective endoscopic oesophagus intervention. The patients must comply with the following criteria in order to be eligible to participate in this clinical study:
- •1\. Male and female, age range \= 18 years without upper age limit
- •2\. ASA classification I ? III
- •3\. Written informed consent
Exclusion Criteria
- •1\. Age range \< 18 years
- •2\. ASA classification IV and V
- •3\. Allergic reaction to planned medication in the patients? medical history
- •4\. Unregulated hypertension
- •5\. Hypovolemia or hypotension (systolic blood pressure \<80 or mean arterial pressure \<50 mmHg)
- •6\. Severe bradycardia (heart rate \< 50/min) and / or related brady\-dysrhythmias (e.g. advanced heart block)
- •7\. Impaired ventricular function (left ventricular ejection fraction \<30%)
- •8\. Impaired renal function, GFR less than 15ml/min or undergoing hemodialysis
- •9\. Impaired liver function
- •10\. Substance abuse
Outcomes
Primary Outcomes
Not specified
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