A Flavonoid-enriched Mediterranean Diet for Multiple Sclerosis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 100
- Locations
- 2
- Primary Endpoint
- Microbiota changes
Study Overview
Brief Summary
This study examines the impact of a Mediterranean diet on individuals with multiple sclerosis (MS). MS is a multifactorial disease in which environmental factors, such as nutrition, can influence disease progression. Therefore, this study aims to investigate whether a healthier dietary pattern, specifically a flavonoid-rich Mediterranean diet, can affect disease parameters.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Sequential
- Primary Purpose
- Supportive Care
- Masking
- None
Eligibility Criteria
- Ages
- 30 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Expanded Disability Status Scale (EDSS): 0-6
Exclusion Criteria
- •Diagnosed digestive pathology
Outcomes
Primary Outcomes
Microbiota changes
Time Frame: Three timepoints, before start of the strict diet (day 14), after the strict diet (day 31), and after the follow-up period of three months (day 122).
Microbiota sequencing on fecal samples to identify the different bacterial strains that are present.
Secondary Outcomes
No secondary outcomes reported
Investigators
Jerome J. A. Hendriks
Prof. Dr. Jerome J.A. Hendriks
Hasselt University