Effect of symbiotic on Immunotherapy
Phase 3
- Conditions
- Perennial allergic rhinitis.Other allergic rhinitis
- Registration Number
- IRCT2015120123235N4
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
patients with persistent allergic rhinitis; Mashhad residents and surrounding towns; Have a positive skin test with Aeroallergen; Cooperate in projects
Exclusion criteria: A history of autoimmune disease; Systemic corticosteroids or immunosuppressive drugs consumption and effective on immune system; Pregnant Women; Patients with immunodeficiency; Patients with malnutrition; Use Antibiotic during synbiotic consumption
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of life. Timepoint: Before the intervention and two month later. Method of measurement: Snot 22 questionnaire.;IL4. Timepoint: Before the intervention and two month later. Method of measurement: Flow cytometry.;T-reg. Timepoint: Before the intervention and two month later. Method of measurement: Flow cytometry.;IFN- gamma. Timepoint: Before the intervention and two month later. Method of measurement: Flow cytometry.
- Secondary Outcome Measures
Name Time Method Systemic reactions to immunotherapy. Timepoint: At every turn immunotherapy. Method of measurement: Clinical.