Comparing the Effectiveness of Buccal Infiltration of Different Volumes of Articaine for Extraction of Mandibular Posterior Teeth- A Randomized Clinical Trial.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 114
- 试验地点
- 4
- 主要终点
- Intensity of pain
研究概览
简要总结
This study compares the effectiveness of two different volumes of buccal infiltration of Articaine for the extraction of mandibular posterior teeth. One group receives buccal infiltration of 1.8 ml of 4% Articaine and the other group receives buccal infiltration of 3.6 ml of 4% Articaine.
详细描述
The most widely and commonly used injection method for the extraction of mandibular posterior teeth is the inferior alveolar nerve block (IANB) technique. However, various complications like pain during injection, transient facial nerve paralysis, trismus, hematoma, and paresthesia are associated with the inferior alveolar nerve block technique.
Local infiltration technique has been proven as a safer and less painful anesthetic injection technique compared to IANB. Unfortunately, the dense nature of cortical bone in the mandibular posterior region hinders sufficient diffusion of anesthetic solution during infiltration. Thus, to achieve an adequate anesthesia for a painless dental extraction of mandibular posterior teeth by infiltration technique, a strong and effective local anesthetic agent having a deeper penetrating property should be used.
Articaine is one of the most widely used local anesthetic agents. It is more potent and has shown more success rate than Lidocaine and Mepivacaine in providing anesthesia in mandibular and maxillary posterior teeth by buccal infiltration diffusibility.
This study compares the effectiveness of two different volumes of buccal infiltration of Articaine for the extraction of mandibular posterior teeth.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All healthy patients (ASA I) or patients with mild systemic disease with no functional limitations (ASA II)
- •Patients aged ≥ 18 years of age.
- •Patients requiring extraction of mandibular posterior teeth including grossly decayed tooth, grade I mobile tooth, root stumps and indicated for therapeutic reasons.
- •Patients not allergic to the drugs or anesthetic agents used in the surgery.
排除标准
- •Acute infection at the extraction site.
- •Patients indicated for surgical extraction of teeth.
- •Patients already taking medications affecting pain assessment.
- •Pregnant patients.
结局指标
主要结局
Intensity of pain
时间窗: From reflection of mucoperiosteum till delivery of tooth out of socket.
VAS scale is a validated scale measuring pain with possible score range from 0 (no pain) to 100 (severe pain).
Time of onset of anesthesia
时间窗: upto 10 minutes
It will be assessed by probing buccal and lingual soft tissue using a dental explorer every 2 minutes after infiltration using a standard digital stop clock.
Presence or absence of pain
时间窗: From reflection of mucoperiosteum till delivery of tooth out of socket.
A 100 mm Numerical rating scale assessing intraoperative pain. Possible score ranges from 0 (no pain) to 100 (worst possible pain).
次要结局
未报告次要终点
研究者
Muhammad Atif Saleem Agwan
Assistant Professor
Qassim University