Control of breathing in systemic sclerosis

Recruiting

• Conditions: skin sclerosis; systemic sclerosis; 10010761; 10013369

• Registration Number: NL-OMON39967
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Patients:
a.age over 18 years
b.a diagnosis of SSC confirmed by criteria of the American Rheumatology Association (ACR criteria 1987)
c.participated in the MRI study (protocol number P11.148);Healthy adult controls:
a. age above 18 years

Exclusion Criteria

Patients:
a. severe left-sided heart failure
b.active psychiater-diagnosed mental disorder, thereby not able to provide informed consent
c.clinical suspicion on current or recent vascular cerebral accident.;Healthy adult controls:
a. no history or symptoms/signs of disease

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1. Hyperoxic ventilatory response to hypercapnia<br /><br>2. Mouth occlusion pressures </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable </p><br>