Cardiac Outcome Measures in Children With Muscular Dystrophy
- Conditions
- Duchenne Muscular DystrophyLimb Girdle Muscular DystrophyBecker Muscular Dystrophy
- Registration Number
- NCT01066455
- Lead Sponsor
- Cooperative International Neuromuscular Research Group
- Brief Summary
The purpose of the research study is to evaluate different cardiac measures that are obtained by echocardiographic tests in patients with muscular dystrophy.
- Detailed Description
The research study will include 50 participants aged 8 to 18 years old (before 18th birthday) with Duchenne, Becker, or autosomal recessive limb-girdle (specifically: LGMD 2C-2F and 2I) muscular dystrophies.
Participants will be seen in one of five Cooperative International Neuromuscular Research Group (CINRG) centers located in the United States.
All study assessments will be completed in the same day and include reviewing past medical and surgical history, collecting vital signs, collecting cardiac measures through echocardiographic tests.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
- Participants must be between the ages of 8 and 18 years old
- Confirmed diagnosis of muscular dystrophy (DMD, BMD, or LGMD 2C-2F and 2I)
- Investigator assessment of inability to comply with protocol
- History of a congenital cardiac defect or other cardiac disease unrelated to muscular dystrophy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (5)
University of Pittsburgh
🇺🇸Pittsburgh, Pennsylvania, United States
University of California Davis
🇺🇸Sacramento, California, United States
Washington University St. Louis
🇺🇸St. Louis, Missouri, United States
Children's National Medical Center
🇺🇸Washington, District of Columbia, United States
Texas Children's Hospital
🇺🇸Houston, Texas, United States