comparison of Letrozole and Clomiphene in combined regimens with gonadotropins in pregnancy rate in pcos patients with clomiphene resistant polycystic ovarian syndrome.
Phase 2
- Conditions
- Clomiphene resistant polycystic ovarian syndrome.Noninflammatory disorders of female genital tract
- Registration Number
- IRCT138810132967N1
- Lead Sponsor
- Vice-chancellor for Research, Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 120
Inclusion Criteria
Clomiphene resistant polycystic ovarian syndrome, age 20-35 years
Exclusion criteria: BMI more than 27, presence of hypothyroidism, hyperprolactinemia, or decreased ovarian reserve, male factor infertility, tubal or uterine factor diagnosed by HSG, peritoneal factor (history of previous surgery)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endometrial thickness. Timepoint: Tenth or eleventh day of menstrual cycle. Method of measurement: Transvaginal sonography.;Ovarian response. Timepoint: Tenth or eleventh of menstrual cycle. Method of measurement: Transvaginal sonography.
- Secondary Outcome Measures
Name Time Method Gonadotropin ampule consuption. Timepoint: Tenth or eleventh of menstrual cycle. Method of measurement: Transvaginal sonography.;Pregnancy rate. Timepoint: Two weeks after HCG injection. Method of measurement: pregnancy test.