The comparative study of combination Gabapentin and topiramate vs treatment alone topiramate or Gabapentin of painful diabetic neuropathy

Not Applicable

• Conditions: Insulin-dependent diabetes mellitus with neurological complications; Diabetic neuropathy.

• Registration Number: IRCT201108287432N1
• Lead Sponsor: Kermanshah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Inclusion criteria included: 1 - diabetes Type II 2 - Dissatisfaction at entering the study, 3 - Failure to receive medication to control pain when the study began, 4 - exposure to neuropathic pain from diabetes.
Exclusion criteria: kidney disease - pregnancy - breastfeeding - a history of liver disease - while taking anti-seizure- taking OCP - a history of sensitivity to Astazvlamydya - other causes for neuropathy, such as MS-CVA

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of painful diabetic neuropathy. Timepoint: Day 15, 30, 60 and 90. Method of measurement: Based on TCSS.

Secondary Outcome Measures

Name	Time	Method
Changes in HbA1c. Timepoint: Day 15, 30, 60, 90. Method of measurement: Based on laboratory assessment.;Changes in triglycerid. Timepoint: Day 15, 30, 60, 90. Method of measurement: based on laboratory assessment.;Changes in cholestrol. Timepoint: Day 15, 30, 60, 90. Method of measurement: based on laboratory assessment.