Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16,000
- 试验地点
- 1
- 主要终点
- Incidence of influenza-like illness (ILI) and COVID-like illness (CLI) in a study participant.
研究概览
简要总结
This is a prospective observational study using a mobile study platform (app) that is designed for use on Android phones. Study participants will provide baseline demographic and medical information and report symptoms of respiratory infection on a weekly basis using the app. Participants will also report use of prevention techniques on the weekly survey. Mobility data will be collected passively using the sensors on the participant's smartphone, if the participant has granted the proper device permissions. The overall goals of the study are to track spread of coronavirus-like illness (CLI), influenza-like illness (ILI) and non-specific respiratory illness (NSRI) on a near-real time basis and identify specific behaviors associated with an increased or decreased risk of developing these conditions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult 18 years or older, Android mobile phone user, Resides in the United States (has a US home address)
排除标准
- •Under the age of 18, Does not use an Android mobile device, Opts out of sharing mobility data, Does not live within the United States
结局指标
主要结局
Incidence of influenza-like illness (ILI) and COVID-like illness (CLI) in a study participant.
时间窗: 6-month participation period
The definition of ILI will be adapted from CDC guidelines as a participant reporting fever in addition to cough or sore throat without any other known cause. All study analyses and outcomes will be reported using federated analytics. Federated analytics utilizes aggregated responses, rather than individual subject reports. Due to this, when reporting the final outcome, the total incidence may not add up to exactly 100%.
Incidence of COVID-like illness (CLI) in a study participant.
时间窗: 6-month participation period
CLI will be defined as fever and cough, or shortness of breath, or loss of smell. Incidence will be defined as reporting of the above symptoms in the 7 days prior (and not previously). All study analyses and outcomes will be reported using federated analytics. Federated analytics utilizes aggregated responses, rather than individual subject reports. Due to this, when reporting the final outcome, the total incidence may not add up to exactly 100%.
次要结局
- Disease Prevalence(1-year study period)
研究者
John Brownstein
Chief Innovation Officer
Boston Children's Hospital