MedPath

EFFICACY AND SAFETY OF NIVOLUMAB IN METASTATIC RENAL CELL CANCER PATIENTS - JAPANESE REAL-WORLD DATA THROUGH CLINICAL CHART REVIEW

Not Applicable
Conditions
Patients with RCC with distant metastasis treated with nivolumab under real clinical practice.
Registration Number
JPRN-UMIN000033312
Lead Sponsor
Bristol-Myers Squibb Ono Pharmaceutical CO.,LTD.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
200
Inclusion Criteria

Not provided

Exclusion Criteria

Patients who have participated in some trials with immuno-checkpoint blockade before or after treatment with nivolumab after diagnosis with RCC.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To describe actual usage and pattern of nivolumab in advanced/metastatic RCC patients in clinical practice; such as treatment frequency, treatment-history before and after nivolumab use, treatment period, treatment line, changes related to management of adverse events (AEs), etc To assess overall effectiveness (overall survival [OS], progression-free survival [PFS], objective response rate [ORR], duration of response [DOR]) and safety of nivolumab in advanced/metastatic RCC patients
Secondary Outcome Measures
NameTimeMethod
Effectiveness and safety by special subgroup; brain metastasis and non-clear cell RCC etc Effectiveness and safety in post-nivolumab treatment; treatment-history, regimen/response/AE etc
© Copyright 2025. All Rights Reserved by MedPath