LSFG-SKIN, Laser Speckle Flowgraphy
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 1
- 试验地点
- 2
- 主要终点
- Imaging Blood Flow
研究概览
简要总结
The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.
详细描述
Laser speckle skin blood flow (LSFG-SKIN) will be recorded in normal subjects and in patients with disorders affecting skin capillary perfusion, which may include cardiovascular disorders, dermatologic disorders, skin wounds, ocular disorders, psychiatric disorders, and neurologic disorders.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •●Healthy normal control subjects ages 18-90
- •Cardiology Subjects
- •Ages 18-90
- •History of dysrhythmia, heart failure, cardiac ischemia, hypertension, peripheral vascular disease
- •Dermatology Subjects
- •Ages 18-90
- •History of inflammatory and cancerous lesions
- •Endocrine Subjects
- •Ages 18-90
- •History of diabetes, thyroid disease
- •Neurology Subjects
- •Ages 18-90
- •History of dementia, headaches, Parkinson's, light sensitivity, stroke, TIA, multiple sclerosis
- •Psychiatry Subjects
- •Ages 18-90
- •History of bipolar, schizophrenia, anxiety, depression
- •Surgery Subjects
- •Ages 18-90
- •History of skin wounds(trauma, chemotherapy, radiation), thermal burns, or plastic and reconstructive surgical procedures.
- •Ophthalmology Subjects
- •Ages 18-90
- •History of ocular disorders caused by hypo perfusion or inflammatory disorders
排除标准
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Cardiology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Dermatology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Endocrine Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Neurology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Psychiatry Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Surgery Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Ophthalmology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
结局指标
主要结局
Imaging Blood Flow
时间窗: One visit
Imaging blood flow in the tissue is of major importance in the clinical environment
次要结局
未报告次要终点
研究者
Randy Kardon
Randy Kardon M.D. Ph.D Professor and Director of Neuro-ophthalmology
University of Iowa