LSFG-SKIN, Laser Speckle Flowgraphy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hypertension
- Sponsor
- Randy Kardon
- Enrollment
- 1
- Locations
- 1
- Primary Endpoint
- Imaging Blood Flow
- Status
- Terminated
- Last Updated
- 2 years ago
Overview
Brief Summary
The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.
Detailed Description
Laser speckle skin blood flow (LSFG-SKIN) will be recorded in normal subjects and in patients with disorders affecting skin capillary perfusion, which may include cardiovascular disorders, dermatologic disorders, skin wounds, ocular disorders, psychiatric disorders, and neurologic disorders.
Investigators
Randy Kardon
Randy Kardon M.D. Ph.D Professor and Director of Neuro-ophthalmology
University of Iowa
Eligibility Criteria
Inclusion Criteria
- •●Healthy normal control subjects ages 18-90
- •Cardiology Subjects
- •Ages 18-90
- •History of dysrhythmia, heart failure, cardiac ischemia, hypertension, peripheral vascular disease
- •Dermatology Subjects
- •Ages 18-90
- •History of inflammatory and cancerous lesions
- •Endocrine Subjects
- •Ages 18-90
- •History of diabetes, thyroid disease
Exclusion Criteria
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Cardiology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Dermatology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Endocrine Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
Outcomes
Primary Outcomes
Imaging Blood Flow
Time Frame: One visit
Imaging blood flow in the tissue is of major importance in the clinical environment