LSFG-SKIN, Laser Speckle Flowgraphy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- Enrollment
- 1
- Locations
- 1
- Primary Endpoint
- Imaging Blood Flow
Study Overview
Brief Summary
The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.
Detailed Description
Laser speckle skin blood flow (LSFG-SKIN) will be recorded in normal subjects and in patients with disorders affecting skin capillary perfusion, which may include cardiovascular disorders, dermatologic disorders, skin wounds, ocular disorders, psychiatric disorders, and neurologic disorders.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •●Healthy normal control subjects ages 18-90
- •Cardiology Subjects
- •Ages 18-90
- •History of dysrhythmia, heart failure, cardiac ischemia, hypertension, peripheral vascular disease
- •Dermatology Subjects
- •Ages 18-90
- •History of inflammatory and cancerous lesions
- •Endocrine Subjects
- •Ages 18-90
- •History of diabetes, thyroid disease
- •Neurology Subjects
- •Ages 18-90
- •History of dementia, headaches, Parkinson's, light sensitivity, stroke, TIA, multiple sclerosis
- •Psychiatry Subjects
- •Ages 18-90
- •History of bipolar, schizophrenia, anxiety, depression
- •Surgery Subjects
- •Ages 18-90
- •History of skin wounds(trauma, chemotherapy, radiation), thermal burns, or plastic and reconstructive surgical procedures.
- •Ophthalmology Subjects
- •Ages 18-90
- •History of ocular disorders caused by hypo perfusion or inflammatory disorders
Exclusion Criteria
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Cardiology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Dermatology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Endocrine Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Neurology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Psychiatry Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Surgery Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
- •Ophthalmology Subjects
- •Cataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.
- •Angle closure glaucoma
Arms & Interventions
Clinic Subjects
cardiology subjects, dermatology subjects, endocrine subjects, neurology subjects, psychiatry subjects, surgery subjects, ophthalmology subjects.
Intervention: laser speckle flowgraphy (Device)
Outcomes
Primary Outcomes
Imaging Blood Flow
Time Frame: One visit
Imaging blood flow in the tissue is of major importance in the clinical environment
Secondary Outcomes
No secondary outcomes reported
Investigators
Randy Kardon
Randy Kardon M.D. Ph.D Professor and Director of Neuro-ophthalmology
University of Iowa