REGistry of Long-term AnTithrombotic TherApy-2
Recruiting
- Conditions
- Atrial Fibrillation
- Registration Number
- NCT04347187
- Lead Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
- Brief Summary
To assess the rates of ischemic and hemorrhagic complications of long-term antithrombotic therapy in patients with atrial fibrillation
- Detailed Description
The register is a Russian prospective single-center observational study of patients who have indications for long-term antithrombotic therapy in connection with atrial fibrillation
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 2000
Inclusion Criteria
- Documented atrial fibrillation with CHA2DS2VASC > 1
Exclusion Criteria
- Subjects who are unwilling or unable to provide informed consent. ACS within 12 months before inclusion Severe CHF (NYHA IV) Stroke within 6 months before inclusion Severe liver or muscle disease Severe kidney disease / renal failure with creatinine > 3 mg/dl Conceivable impossibility to come in touch with the patient or his family at 1-year after the intervention
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method composite of any bleeding events unclusion up to 5 years major, clinically relevant nonmajor, minor (BARC, ISTH,GARFIELD AF)
composite of major cardiovascular events unclusion up to 5 years stroke, myocardial infarction, stent thrombosis \[definite or probable\], or urgent revascularization, cqrdiac death
- Secondary Outcome Measures
Name Time Method Mutations in following genes inclusion CYP2C9\*, VKORC1
Trial Locations
- Locations (1)
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
🇷🇺Moscow, Russian Federation