Study of Mutations of Epidermal Growth Factor Receptor in the Blood of Patients With Advanced Non Small Cell Lung Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Existence of epidermal growth factor receptor (EGFR) mutations in peripheral blood
研究概览
简要总结
RATIONALE: Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
PURPOSE: This laboratory study is looking at epidermal growth factor receptor mutations in the blood of patients with advanced non-small cell lung cancer.
详细描述
OBJECTIVES:
- Determine if epidermal growth factor receptor (EGFR) mutation exists in the peripheral blood of patients with advanced non-small cell lung cancer (NSCLC).
- Estimate the frequency of EGFR mutation in these patients.
- Correlate the presence of EGFR mutation in blood with EGFR mutation in primary or metastatic NSCLC tumor block.
OUTLINE: Patients undergo blood collection for analysis of epidermal growth factor receptor mutation by DNA sequencing.
PROJECTED ACCRUAL: A total of 50 patients will be accrued for this study.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Existence of epidermal growth factor receptor (EGFR) mutations in peripheral blood
时间窗: Day 1
Frequency of EGFR mutation
时间窗: Day 1
Number of participants with EGFR mutation in tissue and plasma.
Number of participants with EGFR mutation in peripheral blood and in tumor tissue.
时间窗: Day 1
次要结局
未报告次要终点