Eplerenone on Top of ACE Inhibition in Chronic Kidney Disease Patients with Hypertension (EPOCH)
- Conditions
- proteinuric patients suffering from chronic kidney disease (II - III) ,diabetes mellitus II and hypertensionTherapeutic area: Body processes [G] - Physiological processes [G07]
- Registration Number
- EUCTR2012-002175-34-AT
- Lead Sponsor
- Med. Univ. Wien, Universitätsklinik f. Innere Medizin III, Abt. f. Nephrologie und Dialyse
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
Chronic kidney disease stages II-III (defined by MDRD formula)
Diabetes mellitus type 2 (defined by WHO criteria)
Urinary albumin to creatinine ratio (UACR) >300mg/g, UACR >200mg/g if already receiving RAS blockade
Hypertension
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 24
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 24
Exclusion Criteria
Age <18 years
UACR >3500mg/g
severe hypertension
pregnancy
unwilling or unability to sign the informed consent
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method