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Work Activity Augmented by Cognitive Rehabilitation for Schizophrenia

Phase 2
Completed
Conditions
Schizoaffective Disorder
Schizophrenia
Registration Number
NCT00430560
Lead Sponsor
VA Office of Research and Development
Brief Summary

This research investigates the benefits of productive activity and cognitive rehabilitation for patients with schizophrenia. Key questions are:

1. does cognitive rehabilitation plus work activity produce better outcomes than work activity alone?

2. Is cognitive rehabilitation more helpful for individuals with moderate or greater cognitive impairment than for individuals without such impairment?

3. Does cognitive rehabilitation reduce the dropout rate and increase participation in work activity for cognitively impaired subjects?

4. What features of cognitive rehabilitation are most important for clinical and rehabilitation outcomes?

Detailed Description

This is a randomized, matching study in which subjects are stratified by degree of cognitive impairment, then randomly assigned to one of two conditions: Work Services Only vs. Work Services plus cognitive rehabilitation. Longitudinal analysis of work activity, work performance, symptoms, quality of life, cognitive function and service utilization are made.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
150
Inclusion Criteria
  • diagnosis of schizophrenia or schizoaffective disorder
Exclusion Criteria
  • change in psychiatric medications or housing within 30 days of study intake
  • episode of drug abuse within 30 days of study intake
  • GAF score 30 or less
  • known neurological disease or developmental disability

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Neuropsychological test performancedata collection completed
Secondary Outcome Measures
NameTimeMethod
Psychiatric symptomsdata collection completed
Quality of lifedata collection completed
Hours workeddata collection completed
Hours of productive activitydata collection completed

Trial Locations

Locations (1)

VA Connecticut Healthcare System

🇺🇸

West Haven, Connecticut, United States

VA Connecticut Healthcare System
🇺🇸West Haven, Connecticut, United States

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