NCT00430560已完成2 期
Work Activity Augmented by Cognitive Rehabilitation: Continuation and Follow-up
适应症
干预措施
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Neuropsychological test performance
研究概览
简要总结
This research investigates the benefits of productive activity and cognitive rehabilitation for patients with schizophrenia. Key questions are:
- does cognitive rehabilitation plus work activity produce better outcomes than work activity alone?
- Is cognitive rehabilitation more helpful for individuals with moderate or greater cognitive impairment than for individuals without such impairment?
- Does cognitive rehabilitation reduce the dropout rate and increase participation in work activity for cognitively impaired subjects?
- What features of cognitive rehabilitation are most important for clinical and rehabilitation outcomes?
详细描述
This is a randomized, matching study in which subjects are stratified by degree of cognitive impairment, then randomly assigned to one of two conditions: Work Services Only vs. Work Services plus cognitive rehabilitation. Longitudinal analysis of work activity, work performance, symptoms, quality of life, cognitive function and service utilization are made.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of schizophrenia or schizoaffective disorder
排除标准
- •change in psychiatric medications or housing within 30 days of study intake
- •episode of drug abuse within 30 days of study intake
- •GAF score 30 or less
- •known neurological disease or developmental disability
研究组 & 干预措施
1
Active Comparator
work therapy
干预措施: work therapy (Procedure)
1
Active Comparator
work therapy
干预措施: work therapy (Behavioral)
2
Experimental
work therapy plus cognitive remediation
干预措施: cognitive rehabilitation (Behavioral)
结局指标
主要结局
Neuropsychological test performance
时间窗: data collection completed
次要结局
- Psychiatric symptoms(data collection completed)
- Quality of life(data collection completed)
- Hours of productive activity(data collection completed)
- Hours worked(data collection completed)
研究者
研究点 (2)
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