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Clinical Trials/NCT00430560
NCT00430560
Completed
Phase 2

Work Activity Augmented by Cognitive Rehabilitation: Continuation and Follow-up

VA Office of Research and Development1 site in 1 country150 target enrollmentOctober 2000
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ConditionsSchizophreniaSchizoaffective Disorder

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Schizophrenia
Sponsor
VA Office of Research and Development
Enrollment
150
Locations
1
Primary Endpoint
Neuropsychological test performance
Status
Completed
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This research investigates the benefits of productive activity and cognitive rehabilitation for patients with schizophrenia. Key questions are:

  1. does cognitive rehabilitation plus work activity produce better outcomes than work activity alone?
  2. Is cognitive rehabilitation more helpful for individuals with moderate or greater cognitive impairment than for individuals without such impairment?
  3. Does cognitive rehabilitation reduce the dropout rate and increase participation in work activity for cognitively impaired subjects?
  4. What features of cognitive rehabilitation are most important for clinical and rehabilitation outcomes?

Detailed Description

This is a randomized, matching study in which subjects are stratified by degree of cognitive impairment, then randomly assigned to one of two conditions: Work Services Only vs. Work Services plus cognitive rehabilitation. Longitudinal analysis of work activity, work performance, symptoms, quality of life, cognitive function and service utilization are made.

Registry
clinicaltrials.gov
Start Date
October 2000
End Date
October 2015
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •diagnosis of schizophrenia or schizoaffective disorder

Exclusion Criteria

  • •change in psychiatric medications or housing within 30 days of study intake
  • •episode of drug abuse within 30 days of study intake
  • •GAF score 30 or less
  • •known neurological disease or developmental disability

Outcomes

Primary Outcomes

Neuropsychological test performance

Time Frame: data collection completed

Secondary Outcomes

  • Psychiatric symptoms(data collection completed)
  • Quality of life(data collection completed)
  • Hours of productive activity(data collection completed)
  • Hours worked(data collection completed)

Study Sites (1)

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