Epidemiological, Clinical, Microbiological and Outcome Description of Patients With Klebsiella sp Meningitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 132
- 试验地点
- 18
- 主要终点
- Characterize meningitis with Klebsiella pneumoniae
研究概览
简要总结
Klebsiella pneumoniae is implicated in the occurrence of severe pneumonia. Most Klebsiella pneumoniae infections are associated with care and occur in patients with compromised immune defenses. More recently, cases of hepatic abscess and acute community meningitis related to strains of Klebsiella pneumoniae have been reported. The mortality of these infections is important, most often due to a delayed diagnosis. The poor prognostic factors reported in the literature for very low numbers are: advanced age, coma, septic shock, glyceryachia <10mg / dL and proteinuria> 750 mg / dL. In addition, no study has specifically focused on the factors of occurrence and factors associated with Klebsiella sp. Indeed, meningitis related to Klebsiella pneumoniae seems to be a rare but probably underestimated event whose risk factors, clinical presentation, microbiological are little known and the treatment modalities of this severe infection are not codified.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Man or Woman whose age ≥ 18 years
- •Patient with meningitis Klebsiella sp., hospitalized in one of the hospitals of the Clinical Microbiology Group
- •Francophone patient
排除标准
- •Patient under tutorship or curatorship
- •Patient deprived of liberty
- •Patient under safeguard of justice
- •Patient opposing his participation
结局指标
主要结局
Characterize meningitis with Klebsiella pneumoniae
时间窗: Day 1
This corresponds to characterize Klebsiella pneumoniae meningitis, portal entry, secondary infection, associated antibiotic and associated therapies and the clinical course of patients.
次要结局
未报告次要终点
