Changes in Renal Papillary Density After Hydration Therapy in Calcium Stone Formers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 主要终点
- Changes in renal papillary density
研究概览
简要总结
Patients with recurrent calcium oxalate stones undergoing endourological procedures for renal stones at our institution from June 2013 to June 2014 were considered eligible for enrolment. Enrolled patients underwent a baseline unenhanced CT scan before the urological procedure; after endoscopic removal of their stones, the patients were instructed to drink at least 2 L/day of a hypotonic, oligomineral water low in sodium and minerals (fixed residue at 180°C <200 mg/L) for at least 12 months. Finally, the patients underwent a follow-up unenhanced CT scan during hydration regimen.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing endourological procedures for renal stones
- •Recurrent stone disease
- •Calcium oxalate stones (>50% of the stone made of calcium oxalate)
排除标准
- •Systemic conditions causing stones (hyperparathyroidism, intestinal malabsorption, renal tubular acidosis)
- •Non-calcium oxalate stones
研究组 & 干预措施
Hydration
Patients were instructed to drink at least 2 L/day of a hypotonic, oligomineral water low in sodium and minerals (fixed residue at 180°C <200 mg/L) for at least 12 months
干预措施: Oligomineral water (Other)
结局指标
主要结局
Changes in renal papillary density
时间窗: At baseline and after 12 months
Renal papillary density measured with unenhanced CT scan
次要结局
未报告次要终点