Changes in Renal Papillary Density After Hydration Therapy in Calcium Stone Formers
Not Applicable
Completed
- Conditions
- Urolithiasis
- Interventions
- Other: Oligomineral water
- Registration Number
- NCT03343743
- Brief Summary
Patients with recurrent calcium oxalate stones undergoing endourological procedures for renal stones at our institution from June 2013 to June 2014 were considered eligible for enrolment. Enrolled patients underwent a baseline unenhanced CT scan before the urological procedure; after endoscopic removal of their stones, the patients were instructed to drink at least 2 L/day of a hypotonic, oligomineral water low in sodium and minerals (fixed residue at 180°C \<200 mg/L) for at least 12 months. Finally, the patients underwent a follow-up unenhanced CT scan during hydration regimen.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- Patients undergoing endourological procedures for renal stones
- Recurrent stone disease
- Calcium oxalate stones (>50% of the stone made of calcium oxalate)
Exclusion Criteria
- Systemic conditions causing stones (hyperparathyroidism, intestinal malabsorption, renal tubular acidosis)
- Non-calcium oxalate stones
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Hydration Oligomineral water Patients were instructed to drink at least 2 L/day of a hypotonic, oligomineral water low in sodium and minerals (fixed residue at 180°C \<200 mg/L) for at least 12 months
- Primary Outcome Measures
Name Time Method Changes in renal papillary density At baseline and after 12 months Renal papillary density measured with unenhanced CT scan
- Secondary Outcome Measures
Name Time Method