a Prospective Study on the Efficacy of Magnifying Endoscopy With Narrow-band Imaging in Diagnosing Gastric Lesions
Completed
- Conditions
- Stomach Neoplasms
- Registration Number
- NCT01508520
- Lead Sponsor
- Xiaobo Li
- Brief Summary
Magnifying endoscopy with narrow-band imaging (ME-NBI) can emphasize surface pattern and microvascular architecture of the gastric mucosa.However,the usefulness and criteria of NBI for differential diagnosis among early gastric cancers (EGC) have not been fully established.The study is based on the hypothesis:
1. ME-NBI is useful in distinguishing EGC from other gastric lesions
2. ME-NBI is useful in further differential diagnosis among EGCs.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 146
Inclusion Criteria
- patients with gastric lesions which were detected by conventional screening endoscopy and suspected of early malignancy.
Exclusion Criteria
- advanced gastric cancer or any other malignancy;
- patients under unsuitable conditions for examination or treatment, such as acute upper gastrointestinal bleeding, noncorrectable coagulopathy, severe systemic disease, etc;
- inability to provide informed consent;
- inability to provide histology of resected specimens after endoscopic treatment or surgery.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method diagnosis accuracy of ME-NBI in 2 weeks after ME-NBI examination ME-NBI diagnosis was made during real-time endoscopy procedure and reviewed in two weeks after ME-NBI examination. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of ME-NBI diagnosis compared with histology were measured.
- Secondary Outcome Measures
Name Time Method