High-risk human papillomavirus (HrHPV) in the population research on cervical cancer: a randomised clinical trial
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Cervical intraepithelial neoplasia
- Sponsor
- Vrije University Medical Centre (VUMC) (The Netherlands)
- Enrollment
- 44102
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
2004 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/15054873 Design, methods and baseline data: 2005 Results article in http://www.ncbi.nlm.nih.gov/pubmed/15900579 Association between higher-grade CIN and HPV type 2007 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/17919718 5-year follow-up 2012 Results article in http://www.ncbi.nlm.nih.gov/pubmed/22177579 Final results 2018 Other publications in https://www.ncbi.nlm.nih.gov/pubmed/29663363 Post hoc analysis of 14-year follow-up data 2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/36306283/ Association between cervical precancer risk at 14 years and previous screening results (added 31/10/2022)
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Women invited for the cervical cancer screening program (ages 30 \- 60 years)
- •2\. Residing in either the region covered by district health authority Amstelland\-de Meerlanden and Zuid\-Kennemerland
Exclusion Criteria
- •1\. Not called for screening, ie ages under 30 years, or over 60 years
- •2\. Follow\-up of previous non\-normal cytology within the current screening round of the program, i.e., abnormal cytology or CIN lesions less than two years before inclusion
- •3\. Status after extirpation of the uterus or amputation of the portio
Outcomes
Primary Outcomes
Not specified