Comparative study of morphine effect by intranasal and intravenous methods in orthopedic surgeries
Not Applicable
- Conditions
- Orthopedic surgeries on the upper limbs.
- Registration Number
- IRCT20210328050784N1
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 78
Inclusion Criteria
Candidate for orthopedic surgery for upper limb fractures under general anesthesia
Agree to participate in the study
Natural GCS (score 15) based on the Glasgow scale
Weight between 60 to 100 kg
Duration of operation up to 3 hours
No underlying diseases including diabetes, liver and kidney disease, COPD and coagulation disorders
Lack of sensitivity to drugs
No addiction
No head injuries during the accident
More than 12 breaths per minute
Systolic blood pressure greater than 110 mm Hg
SPO2 More than 95% in room air
Exclusion Criteria
Dissatisfaction with continuing to participate in the project
Prolongation of surgery time more than 3 hours
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative pain. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: VAS scale.;Nausea. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: VAS Nausea Scale.;Vomiting. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: Frequent vomiting: Less than once: Mild,Between 1-3 times: Medium,More than 3 times or howling: severe.;Itching. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: Asking: yes / no.;Vertigo. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: Asking: yes / no.
- Secondary Outcome Measures
Name Time Method