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Clinical Trials/NCT04655859
NCT04655859CompletedNot Applicable

Evaluation of Saliva Thiol/Disulfide Homeostasis and Oxidative Stress in Children With Severe Early Childhood Caries by a Novel Method- Part 1

Kahramanmaras Sutcu Imam University1 site in 1 country80 target enrollmentStarted: May 10, 2020Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
80
Locations
1
Primary Endpoint
thiol/disulfide homeostasis

Study Overview

Brief Summary

The aim of this study was to evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
3 Years to 5 Years (Child)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • 3-5 years

Exclusion Criteria

  • the children with systemic illness, using anti-inflammatory drug

Outcomes

Primary Outcomes

thiol/disulfide homeostasis

Time Frame: six months

Unstimulated saliva samples were taken from all children. Then, thiol/disulfide homeostasis and antioxidant levels were evaluated.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Kahramanmaras Sutcu Imam University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Aslı Sogukpınar

Dr.

Kahramanmaras Sutcu Imam University

Study Sites (1)

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