Diagnostic Value of Smartphone Video in Epileptic Seizures

• Conditions: Value of Smartphone in Epilepsy

• Registration Number: NCT05574725
• Lead Sponsor: Assiut University

Brief Summary

1. Accuracy of seizure diagnosis based on smartphone seizure semiology anaysis

2. Assess the factors that affect the diagnostic reliability of smartphone videos

Detailed Description

E pilepsy has a substantial global burden of disease.1 Diagnosis is made clinically based on a historical recount of witnessed events and a laboratory assessment. Differential diagnosis for seizures is broad. Even seasoned clinicians can be misled when individuals lack medical knowledge or pertinent terminology to accurately represent witnessed seizure behavior.2Video electroencephalogram (EEG) monitoring (VEM) is recommended when there is diagnostic uncertainty in classifying seizure type or epilepsy syndrome.3 Video EEG monitoring provides objective evidence for definitive diagnosis4 ;Additionally, VEM may not be practical for some patients because of relative infrequency of events Geographic limitations, transportation constraints, and insurance coverage may also restrict access.2,4 While VEM is the criterion standard for seizure diagnosis, web-based smartphone use has become a popular means to augment clinical practice involving seizure reporting by people with epilepsy. However, smartphone videos are not recorded in a controlled environment in which the clinicians themselves are able to define when and how each spell is to be recorded,. As such, there are issues of focus, lighting, duration, and initiation that must be considered when interpreting homemade smartphone video recordings obtained by a lay population of caregivers to evaluate people with seizures on the other hand, it has been proven that discriminating seizure's semiology is a learned skill and requires specific neurologic training 11We hypothesize that outpatient smartphone videos predictive value in patients referred for evaluation of epilepsy is variable and depends on multiple factors such as seizure semiology, and interpreting physician . on the other hand, there is no consensus on quality standards and safety recommendation of smartphone videos.

Study Timeline

• Status Verified: 2022-08
• Study First Submitted: 2022-10-07
• Study First Submitted QC: 2022-10-07
• Last Update Submitted: 2022-10-07
• Study First Posted: 2022-10-10
• Last Update Posted: 2022-10-10
• Study Start: 2022-10-20
• Primary Completion: 2022-10-20
• Study Completion: 2023-10-20

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 84

Inclusion Criteria

1. Patients were included in the study at any age
2. provided voluntary consent, completed an HP,
3. submitted an outpatient smartphone video of their primary ictal event, underwent inpatient VEM,

Exclusion Criteria

1. Patients were exclude, pregnant women
2. had an incomplete/absent HP, had no smartphone video,
3. did not undergo VEM, had a confirmed history of mixed epileptic and nonepileptic events (based on prior VEM), declined study participation, or did not provide informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of the predictive value of outpatient smartphone videos in diagnosis of epileptic seizures	1 year	Measures of performance (accuracy, sensitivity, specificity, positive predictive value, and negative predictive value) for smartphone video-based diagnosis by general neurologist and epileptogist (the index test) were compared with those for history and physical examination and video electroencephalogram monitoring (the reference standard).

Secondary Outcome Measures

Name	Time	Method
Assessment of the predictive value of outpatient smartphone videos in diagnosis of epileptic seizures	1year	descriptive analysis of factors affecting quality of smartphone videos