Pre-operative volume replacement versus usual care in diabetic patients having coronary artery bypass graft (CABG) surgery: a randomised controlled trial

niversity Hospitals Bristol NHS Foundation Trust (UK)0 sites169 target enrollmentOctober 29, 2008

Overview

Registry

who.int

Start Date

October 29, 2008

End Date

August 31, 2014

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

niversity Hospitals Bristol NHS Foundation Trust (UK)

•Current inclusion criteria as of 15/05/2009:
•1\. Patients with diagnosed type I or type II diabetes, being treated with oral medication and/or insulin (i.e. not diet controlled only)
•2\. Both males and females, age \>16 and \<80 years
•3\. Undergoing elective or urgent, isolated first time coronary artery bypass graft (CABG) with or without cardiopulmonary bypass (CPB)
•4\. Left ventricular ejection fraction \>\=30%
•Previous inclusion criteria:
•1\. Patients with diagnosed type I or type II diabetes
•2\. Both males and females, aged greater than 16 and less than 80 years
•3\. Undergoing elective or urgent, isolated first time coronary artery bypass graft (CABG) with or without cardiopulmonary bypass (CPB)
•4\. Left ventricular ejection fraction greater than or equal to 25%

•1\. Patients who have had previous cardiac surgery
•2\. Emergency or salvage operation
•3\. Chronic renal failure requiring dialysis
•4\. Current congestive heart failure
•5\. Left ventricular ejection fraction \<30% (i.e. poor LV function)
•Please note that the 5th exclusion criterion was updated as of 15/05/2009\. The previous criterion was as follows:
•5\. Left ventricular ejection fraction less than 25%