A Comparison Between Continuous Versus Intermittent Bolus Infusion of Paravertebral Blocks for Thoracic Surgery: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Opioid consumption 24 hours postoperatively
研究概览
简要总结
The researchers are trying to determine pain medication consumption in the first 24 hours after surgery in patients given the standard continuous infusion of local anesthetic versus patients given the same total dose via programmed intermittent dosing. Both groups will receive the option of patient controlled pain medication as well as the same dose of pre-programmed pain medication. The only difference is the rate of administration: continuous vs. hourly intervals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Investigator)
盲法说明
Investigators will not have direct access to settings on the pump
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Documentation of planned thoracic surgery for which a paravertebral catheter is indicated based on surgeon request as well as appropriateness of location of surgical site.
- •Ability for subject to comply with the requirements of the study.
排除标准
- •Pregnancy.
- •Coagulopathy at time of evaluation or surgery.
- •Infection at the site of needle insertion.
- •Allergy to local anesthetic.
- •Patient refusal.
- •Chronic opioid use
研究组 & 干预措施
Programmed Intermittent Bolus
6 mL 0.2% ropivacaine hourly, starting on arrival to PACU, given via an hourly programmed bolus
干预措施: Programmed Intermittent Bolus (Other)
Continuous Infusion
6 mL 0.2% ropivacaine hourly, starting on arrival to PACU, given via continuous infusion
干预措施: Continuous Infusion (Other)
结局指标
主要结局
Opioid consumption 24 hours postoperatively
时间窗: first 24 hours postoperatively
morphine equivalents of opioids in mg will be obtained from medical record
次要结局
- Opioid consumption 48 hours postoperatively(first 48 hours postoperatively)
研究者
Elird Bojaxhi, M.D.
Principal Investigator
Mayo Clinic