Effect of platelet activating factor receptor antagonist on acute ischemic and its anti-thrombotic and anti-inflammatory mechanism:a case-control study

Zhaoqing First People's Hospital0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1) Diagnosis of an acute ischemic stroke was confirmed using brain magnetic resonance imaging within the onset time=72 hours;
•2) signs and symptoms of neurological deficit, and duration > 6 hours;
•3) National Institutes of Health Stroke Scale (NIHSS) score of patient at admission >= 3;
•4) Age:18 to 90 years-old.

•1) Intracranial hemorrhagic identified by admission computed tomography (CT) scan or bleeding tendency;
•2) Platelet count < 100 x 10^9/L, or > 450 x 10^9/L in the peripheral blood;
•3) Coexisting severe systemic diseases, including severe heart diseases, hepatic and renal insufficiency, cancers, blood diseases or autoimmune diseases;
•4) Major surgery in recent 4 weeks;
•5) History of using other non-steroidal anti-inflammatory drugs, such as cilostazol, dipyridamole, warfarin, new oral anticoagulant drugs (NOACs) and low molecular weight heparin;
•6) Administration of intravenous thrombolysis or/and intra-arterial thrombectomy treatment;
•7) Ginkgo diterpene lactones contraindications.

发起方

Zhaoqing First People's Hospital