NL-OMON56057招募中3 期
Substantially improving the cure rate of high-risk BRCA1-like breast cancer patients with personalized therapy (SUBITO) an international randomized phase III trial - SUBITO
ederlands Kanker Instituut0 个研究点目标入组 94 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 94
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- Women and men with stage III adenocarcinoma of the breast harboring signs of
- •a breast cancer with features of homologous recombination deficiency (HRD)
- •- Age of 18-65 years
- •- The tumor must be HER2-negative
- •- Eastern Cooperative Oncology Group (ECOG) performance status 0-1
排除标准
- •- Distant metastases
- •- Previous radiation therapy
- •- Previous chemotherapy
- •- Any previous treatment with a PARP-inhibitor, including olaparib
- •- Pre-existing neuropathy from any cause in excess of Grade 1
- •- Chronic concomitant use of known strong or moderate CYP3A inducers
研究者
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