Comparing two methods of measuring heart performance

Not yet recruiting

Conditions: Patients requiring advanced hemodynamic monitoring during surgery

Brief Summary: This is a single blind, prospective, observational, single arm, single centric, cohort study comparing the conventional cardiac output monitor Vigileo TM and IAP (Invasive arterial pressure) combination with the new smartphone based application Capstesia TM and CNAP (Continuous non invasive arterial pressure) combination in 50 consecutive adult patients undergoing major surgery requiring cardiac output monitoring. The primary outcome measure will be cardiac output measured by Capstesia TM at time points 5, 10 , 15, 20, 25, 30, 35, 40 , 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 105, 110, 115, 120 minutes post surgical incision. The secondary outcome measure would be the Pulse pressure variation (PPV) measured by Capstesia TM at time points 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 105, 110, 115, 120 minutes post surgical incision.

Recruitment & Eligibility

Inclusion Criteria

1. ASA physical status II and III 2) Adult patients (18.
75 yrs) of age 3) Either sex 4) Patients with a clinical need for invasive arterial pressure (IAP) monitoring 5) Expected duration of anesthesia > 120 min 6) Body mass index (BMI) between 18.5.
30.0 kg/m2 7) Weight between 45.

Exclusion Criteria

Patients with advanced dysfunction of peripheral perfusion (e.g. arterial peripheral artery occlusive disease, Raynaudâ€™s syndrome), arteriovenous shunts for hemodialysis 2) Any history of vascular surgery of the upper extremities 3) History of cardiac arrhythmia 4) Refusal to provide informed consent.

Primary Outcome Measures

Name	Time	Method
Cardiac Output measured by CNAP/ Capstesia combination	5 mins, 10 mins, 15 mins, 20 mins, 25 mins, 30 mins, 35 mins, 40 mins, 45 mins, 50 mins, 55 mins, 60 mins, 65 mins, 70 mins, 75 mins, 80 mins, 85 mins, 90 mins, 95 mins, 100 mins, 105 mins, 110 mins, 115 mins, 120 mins

Secondary Outcome Measures

Name	Time	Method
Pulse Pressure Variation (PPV) measured by Capstesia	5 mins, 10 mins, 15 mins, 20 mins, 25 mins, 30 mins, 35 mins, 40 mins, 45 mins, 50 mins, 55 mins, 60 mins, 65 mins, 70 mins, 75 mins, 80 mins, 85 mins, 90 mins, 95 mins, 100 mins, 105 mins, 110 mins, 115 mins, 120 mins

Locations (1): Rajiv Gandhi Cancer Institute and Research Centre Sector-5; Rohini; New Delhi - 110085
🇮🇳
West, DELHI, India
Rajiv Gandhi Cancer Institute and Research Centre Sector-5; Rohini; New Delhi - 110085
🇮🇳West, DELHI, India
Dr Anamika Kansal
Principal investigator
9466053123
anamikakansal89@gmail.com