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Biofeedback Vs Electrical Stimulation in Treatment of Fecal Incontinence

Not Applicable
Completed
Conditions
Fecal Incontinence
Encopresis
Fecal Soiling
Interventions
Device: Electrical stimulation
Device: Biofeedback
Other: Traditional treatment
Registration Number
NCT04380571
Lead Sponsor
Cairo University
Brief Summary

Fecal incontinence is one of the most psychological frustrating problems. It occurs in children due to many causes. There is a wide range of non-invasive therapeutic approaches like Kegel exercise, Biofeedback, and posterior tibial nerve stimulation. However, up till now, there are no established guidelines for treatment.

the objective of this study is to evaluate and compare the early effect of Biofeedback therapy versus bilateral transcutaneous posterior tibial nerve stimulation (TPNS) as non-invasive methods in the treatment of functional non-retentive fecal incontinence (FNRFI) in children.

Detailed Description

Functional non-retentive fecal incontinence (FNRFI) requires prolonged treatment with a wide range of non-invasive therapeutic approaches like Kegel exercise, Biofeedback, and posterior tibial nerve stimulation (PTNS). However, up till now, there are no established guidelines for treatment.1 The aim of this study is to evaluate and compare the early effect of Biofeedback therapy versus bilateral transcutaneous posterior tibial nerve stimulation (TPTNS) as non-invasive methods in the treatment of (FNRFI) in children.

Methodology: The current prospective randomized controlled study included 93 children with FNRFI who were randomly divided and allocated into three groups. Group A treated by conventional methods through dietetic regulation and Kegal exercises. Group B treated by biofeedback therapy while group C received bilateral (TPTNS). Initial manometric findings including resting pressure, squeeze pressure, 1st sensation, 1st urge, and intense urge were recorded and repeated after 3 and 6 months together with incontinence score recorded in using St' Mark's (Varizey) with the primary endpoint of improvement of the incontinence score more than 50%.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
93
Inclusion Criteria
  • FecaI incontinence
  • Normal defecation frequency,
  • Normal bowel habits and
  • Normal stool consistency
Exclusion Criteria
  • Children who are not cooperative,
  • Children with traumatic sphincter injury,
  • Children with fecal impaction,
  • Children with spinal diseases causing incontinence,
  • Children with anorectal malformation,

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Electrical StimulationElectrical stimulationBilateral (TPTNS); was applied with an electrode above the medial malleolus A second electrode) was applied just below the same malleolus. Electrical stimulation with a low-frequency current (10 Hz), and adjustable intensity. The procedure was done for 20-30 minutes, three times per week for 3 months together with the conventional maneuvers applied in the control group.
BiofeedbackBiofeedbackBiofeedback therapy in addition to the conventional measures done in the control Group. It was performed in the same position used for baseline manometry. The used protocol included strength and sensory training, twice weekly for 3 months. Strength training was performed by a double-lumen rectal PVC balloon clothed catheter (MMS U-72210).
Control groupTraditional treatmentwere managed by conventional methods through Kegal exercises and dietetic regulation where they had received bulky food including vegetables, fruits bran and cereals. Fast foods, spicy drinks and caffeine should be limited in child's diet. Local hygiene and zinc oxide application to the perianal skin were advised to prevent skin excoriation.
Primary Outcome Measures
NameTimeMethod
Incontinence score using St' Mark's (Vaiszey)3 months after intervention

Questionnaire ranging from zero (indicating complete continence) to 24 (indicating total incontinence).

incontinence score using St' Mark's (Vaiszey)6 months after intervention

Questionnaire ranging from zero (indicating complete continence) to 24 (indicating total incontinence).

Secondary Outcome Measures
NameTimeMethod
Resting pressure (mm hg)6 months after intervention

Pressure during relaxation of the anal sphincter

First sensation (volume of the balloon by cm water)6 months after intervention

First sensation of the stool in the rectum

Intense urge (volume of the balloon by cm water)6 months after intervention

the Patent can no longer control the defecation

First Urge(volume of the balloon by cm water)6 months after intervention

The patient is trying to hold defecation and he can

Squeeze pressure (mm hg)6 months after intervention

Pressure during contraction of the anal sphincter

Trial Locations

Locations (1)

Banha University

🇪🇬

Banhā, Banha, Egypt

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