Validation of Uptake of a VEGF-targeted Optical Fluorescent Imaging Tracer in Surgical Specimens of Breast Cancer and Application of Pre- and Intra-operative Human Molecular Fluorescence Imaging Techniques. A multicenter feasibility study - VEGF-Targeted Fluorescent Tracer Imaging in Breast Cancer

niversitair Medisch Centrum Groningen0 个研究点目标入组 20 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

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•Age >= 18 years.
•Patients with proven breast cancer (cytology, histology) who are scheduled to receive operation intervention.
•Tumor size of at least 5 mm (0,5 cm) diameter according to anatomical imaging data.
•Signed written informed consent.
•Able to comply with the protocol.
•WHO performance score 0-2.

•- Other invasive malignancy.
•- Serious other medical conditions.
•- Pregnant or lactating women. (Documentation of a negative pregnancy test must be available for pre-menopausal women with intact reproductive organs and for women less than two years after menopause).
•- Prior radiotherapy on the involved area.
•- Major surgery within 28 days before the initiation of the study.
•- Prior allergic reaction to immunoglobulins or immunoglobulin allergy.
•- Prior neo-adjuvant chemotherapy.
•- Breast prosthesis in target breast.

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