Validation of Uptake of a VEGF-targeted Optical Fluorescent Imaging Tracer in Surgical Specimens of Breast Cancer and Application of Pre- and Intra-operative Human Molecular Fluorescence Imaging Techniques. A multicenter feasibility study
- Conditions
- Breast cancer10006291
- Registration Number
- NL-OMON39185
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Age >= 18 years.
Patients with proven breast cancer (cytology, histology) who are scheduled to receive operation intervention.
Tumor size of at least 5 mm (0,5 cm) diameter according to anatomical imaging data.
Signed written informed consent.
Able to comply with the protocol.
WHO performance score 0-2.
- Other invasive malignancy.
- Serious other medical conditions.
- Pregnant or lactating women. (Documentation of a negative pregnancy test must be available for pre-menopausal women with intact reproductive organs and for women less than two years after menopause).
- Prior radiotherapy on the involved area.
- Major surgery within 28 days before the initiation of the study.
- Prior allergic reaction to immunoglobulins or immunoglobulin allergy.
- Prior neo-adjuvant chemotherapy.
- Breast prosthesis in target breast.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method