Intervention with concentrated albumin for resuscitation of undifferentiated sepsis - Multi Day
- Conditions
- sepsisInfection - Other infectious diseasesEmergency medicine - Resuscitation
- Registration Number
- ACTRN12624000327583
- Lead Sponsor
- Royal Brisbane and Women's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 324
Adult ED patients (greater than or equal to 18 years) with:
1)Systolic blood pressure (SBP) <90mmHg within 8 hours of triage (or lactate greater than or equal to 4)
2)Proven or presumed infection. Patients with presumed infection will be those where the treating senior treating emergency physician deems infection the most likely cause for the patient presentation
1)Jehovah’s Witness
2)Known adverse reaction to albumin administration
3)Terminal state - death seems imminent and inevitable
4)Pathological conditions in which albumin administration is clinically indicated (hepatic cirrhosis with ascites, intestinal malabsorption syndrome, nephrotic syndrome)
5)Acute congestive heart failure
6)Acute head injury
7)Inter-hospital transfer
8)Prior enrolment in the trial within the past 90 days
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method