Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain

Not Applicable

Not yet recruiting

• Conditions: Efficacy of Hemostatic Agents; Partial Pulpotomy; Postoperative Pain
• Interventions: Drug: Sodium Hypochlorite 2,5%; Drug: Chlorhexidine; Drug: Cold Saline

• Registration Number: NCT07058727
• Lead Sponsor: Cukurova University

Brief Summary

This randomized clinical trial evaluates the efficacy of sodium hypochlorite (NaOCl), chlorhexidine (CHX), and cold saline as hemostatic agents in partial pulpotomy. The study compares postoperative pain (via VAS scores) and pulp survival (via clinical/radiographic evaluation) at 1, 3, 7 days, 6 months, and 12 months

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-06-19
• Study First Submitted QC: 2025-06-30
• Status Verified: 2025-07
• Study First Posted: 2025-07-10
• Last Update Submitted: 2025-07-14
• Last Update Posted: 2025-07-17
• Study Start: 2025-08-01
• Primary Completion: 2026-02-01
• Study Completion: 2026-08-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• Permanent teeth with carious pulp exposure (no spontaneous pain).
• Positive vitality test (Endo-Ice).
• No periapical radiolucency.

Exclusion Criteria

• Systemic diseases affecting healing.
• Pregnancy.
• Non-vital pulp/necrosis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Arm 1	Sodium Hypochlorite 2,5%	2.5% NaOCl applied for 1 min after pulp exposure.
Arm 2	Chlorhexidine	2% CHX applied for 1 min
Arm 3	Cold Saline	Hemostasis achieved with 4°C saline for 1 min.

Primary Outcome Measures

Name	Time	Method
Postoperative Pain	1 week	The patient will be asked to rate the pain on the 1st, 3rd and 7th day according to VAS (min skor 0 , max skor 10)
Pulp Survival Rate	12 months	The pulp is expected to be vital, without percussion tenderness and without spontaneous pain

Secondary Outcome Measures

Name	Time	Method
Clinical Success	12 months	Maintaining the integrity of the restoration No need for endodontics treatments