Adityapaka Guggulu and Basti(Enema) in Sandhigatavata(Osteoarthritis)

Phase 2/3

Completed

• Conditions: Osteoarthritis of knee, unspecified. Ayurveda Condition: SANDHIGATAVATAH,

• Registration Number: CTRI/2021/07/034569
• Lead Sponsor: Government PG Ayurveda College and Hospital Varanasi

Brief Summary

In this clinical Study, patients Suffering  from Sandhigata vata were selected from OPD and IPD of Government PG Ayurveda College and Hospital, varanasi, 221002.

Patients between age group 40-70 years, both gender, having clinical signs and symptoms of Sandhigatavata were kept in Inclusive Criteria

Patients having any complications, serious illness like Diabetes mellitus, Tuberculosis, Hypertension etc were kept in Exclusive Criteria

90 patients were randomly assigned in 3 groups.

In Group 1: 30 patients were administered with Adityapaka Guggulu in a dose of 500 mg (2 tab) Bd after food for 2 months.

In Group 2:  30 patients were administered with Dasamuladi Niruha Basti for 16 days. Two schedules of Basti were given at an interval of 1 months for 2 months.

In Group 3: 30 patients were administered with both Aditypaka guggulu and Dasamuladi Niruha basti for 2 months.

Follow up was done after 15 days of completion of treatment.

In this study, Hb%, ESR, and  S. calcium showedimprovement in all three groups.

All three groups showed statistically highly significantimprovement in subjective parameters after therapy. But maximum improvement wasobserved in Group 3 i.e. 50% patients, who were treated with *DasamuladiNiruha  Basti*and *Adityapaka Guggulu* ascompared to Group 2 and Group 1 with 33.33% and 26.67% maximum improvementrespectively.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-07
• Last Update Posted: 2022-10-12

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Patients having the signs and symptoms of Sandhigatavata as described in Ayurvedic texts were selected for clinical trial.
• Patients giving clinical history of Osteoarthritis.
• The diagnosis will be confirmed by x-ray examination of the involved joint wherever possible.

Exclusion Criteria

• Patients having any complications.
• Patients having any other serious illness.(Diabetes mellitus, tuberculosis, hypertension, cancer etc.) 3.
• Patients having any other type of arthritis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in pain and all symptoms in sandhigata vata	2 months

Secondary Outcome Measures

Name	Time	Method
No recurrence of signs and symptoms.	2 months

Trial Locations

Locations (1)

Government PG Ayurveda College and Hospital, Varanasi; 🇮🇳 Varanasi, UTTAR PRADESH, India

Government PG Ayurveda College and Hospital, Varanasi

🇮🇳Varanasi, UTTAR PRADESH, India

Dr K K Dwivedi

Principal investigator

9336913142

dwivedikk@rediffmail.com