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临床试验/CTRI/2021/07/034569
CTRI/2021/07/034569已完成2/3 期

A Clinical Study to evaluate efficacy of Adityapaka Guggulu and Dasamuladi Niruha Basti in Sandhigatavata

Government PG Ayurveda College and Hospital Varanasi1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2021年5月7日最近更新:

试验速览

阶段
2/3 期
状态
已完成
发起方
入组人数
90
试验地点
1
主要终点
Reduction in pain and all symptoms in sandhigata vata

研究概览

简要总结

In this clinical Study, patients Suffering  from Sandhigata vata were selected from OPD and IPD of Government PG Ayurveda College and Hospital, varanasi, 221002.

Patients between age group 40-70 years, both gender, having clinical signs and symptoms of Sandhigatavata were kept in Inclusive Criteria

Patients having any complications, serious illness like Diabetes mellitus, Tuberculosis, Hypertension etc were kept in Exclusive Criteria

90 patients were randomly assigned in 3 groups.

In Group 1: 30 patients were administered with Adityapaka Guggulu in a dose of 500 mg (2 tab) Bd after food for 2 months.

In Group 2:  30 patients were administered with Dasamuladi Niruha Basti for 16 days. Two schedules of Basti were given at an interval of 1 months for 2 months.

In Group 3: 30 patients were administered with both Aditypaka guggulu and Dasamuladi Niruha basti for 2 months.

Follow up was done after 15 days of completion of treatment.

In this study, Hb%, ESR, and  S. calcium showedimprovement in all three groups.

All three groups showed statistically highly significantimprovement in subjective parameters after therapy. But maximum improvement wasobserved in Group 3 i.e. 50% patients, who were treated with DasamuladiNiruha  Bastiand Adityapaka Guggulu ascompared to Group 2 and Group 1 with 33.33% and 26.67% maximum improvementrespectively.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
40.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients having the signs and symptoms of Sandhigatavata as described in Ayurvedic texts were selected for clinical trial.
  • Patients giving clinical history of Osteoarthritis.
  • The diagnosis will be confirmed by x-ray examination of the involved joint wherever possible.

排除标准

  • Patients having any complications.
  • Patients having any other serious illness.(Diabetes mellitus, tuberculosis, hypertension, cancer etc.)
  • Patients having any other type of arthritis.

结局指标

主要结局

Reduction in pain and all symptoms in sandhigata vata

时间窗: 2 months

次要结局

  • No recurrence of signs and symptoms.(2 months)

研究者

发起方
Government PG Ayurveda College and Hospital Varanasi
申办方类型
Research institution and hospital

研究点 (1)

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