Treg to Th17 conversion in the dynamics of inflammation of the human skin. - Treg to Th17 conversion in the human skin.

niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•Healthy volunteers must meet the following criteria:
•Adults older than 18 years of age
•Volunteers must be willing to give a written informed consent
•Volunteers must be able to adhere to the visit schedule;Patients must meet the following criteria:
•Adults older than 18 years of age
•All patients have to have actinic keratosis
•The doctor and the patient decided that the best treatment option is field-treatment with imiquimod 5%
•Patients must be willing to give a written informed consent
•Patients must be able to adhere to the visit schedule

•Volunteers will be excluded from this study when any of the following criteria listed below are met:
•Children or adolescents younger than 18 years of age
•Volunteers with a history or signs of psoriasis
•Volunteers with a history or signs of other inflammatory skin diseases, for example atopic dermatitis
•Volunteers exposed to large amounts of sunlight or UV-radiation in the last week
•Volunteers using immunosuppressive agents like prednisone or methotrexate
•Volunteers with relevant co-morbidities
•Volunteers with a current condition involving an activated immune system, such as the flue or a recent vaccination;Patients will be excluded from this study when any of the following criteria listed below are met:
•Children or adolescents younger than 18 years of age
•Patients with a history or signs of psoriasis
•Patients with a history or signs of other inflammatory skin diseases, for example
•atopic dermatitis
•Patients exposed to large amounts of sunlight or UV-radiation in the last week
•Patients using immunosuppressive agents like prednisone or methotrexate
•Patients with relevant co-morbidities
•Patients with a current condition involving an activated immune system, such as the
•flue or a recent vaccination

发起方

niversitair Medisch Centrum Sint Radboud