The effects of Zinc, vitamin D supplementation and co-supplementation of them versus placebo on adipokines and indicators related to metabolism in over weight and obese subjects
Phase 3
Recruiting
- Conditions
- Obesity.Obesity due to excess calories
- Registration Number
- IRCT201608082365N13
- Lead Sponsor
- Vice Chancellor of Research, Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
age between 20 to 60 years old; BMI greater than 27; willing to participate; weight stable in 3 last months. Exclusion criteria: having a history of coronary artery disease; acute or chronic renal failure; acute or chronic hepatic failure; presence of any chronic inflammatory and autoimmune disease; and any known malignancy; hormone therapy; other non-pathological exclusion criteria included pregnancy; breast feeding; post-menopause; smoking, professional athlete; uncontrolled thyroid disorder; use of medications for dyslipidemia or hypertension; having a special diet for any reason prescribed by the clinic dietitian; consumption of nutritional supplements within the past 12 weeks.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum level of leptin. Timepoint: Before and 12 weeks after intervention. Method of measurement: Serum concentration of leptin with Laboratory Kit.
- Secondary Outcome Measures
Name Time Method Insulin-like growth factor-1. Timepoint: Before and 12 weeks after intervention. Method of measurement: Serum concentration with Laboratory Kit (Mediagnose; Germany).