An observational study to see changes in Lipid profile in different subclasses of Hypothyroid patients according to their TSH level.
Not Applicable
- Conditions
- Health Condition 1: E038- Other specified hypothyroidism
- Registration Number
- CTRI/2023/03/050880
- Lead Sponsor
- ALL INDIA INSTITUTE OF MEDICAL SCIENCES, PATNA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patientâ??s age group 18-65 years with non-specific symptoms (untreated) suggestive of hypothyroidism.
Exclusion Criteria
1.Subjects with previous history of thyroid diseases, such as overt
hyper/hypothyroidism, thyroid
cancer and thyroid nodules.
2.Chronic medical illness or previous surgery pertaining to thyroid.
3.Subjects taking medications affecting thyroid hormone levels such as
thyroid supplementation
and antithyroid agents, and hypolipidemic agents like statins, oral
contraceptive pills.
4.Pregnancy.
5.Diabetes Mellitus.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To determine the level of correlation of cut off values of TSH in relation to dyslipidaemia, hsCRP, anti TPO and anti TG in Hypothyroid, Sub clinical Hypothyroid and two Groups of Biochemically euthyroid patients. <br/ ><br>2.To revaluate the cut off values of TSH based on the association of biochemical parameters observed. <br/ ><br>Timepoint: As Observational Study so from the time of recruitment ( 0 months) till the study period allocated i.e. July 2024, patients will be tested for the above parameters and results will be analysed without follow up.
- Secondary Outcome Measures
Name Time Method 1.To access the association of signs and symptoms suggestive of hypothyroidism using the ZULEWSKI score.Timepoint: As Observational Study so from the time of recruitment ( 0 months) till the study period allocated i.e. July 2024, patients will be tested for the above parameters and results will be analysed without follow up.