Use of Fish Oils to Reduce Recurrence of Atrial Fibrillation Following DC Cardioversion
- Registration Number
- NCT00232219
- Lead Sponsor
- Melbourne Health
- Brief Summary
The purpose of this study is to investigate whether fish oil supplements may be beneficial in preventing the recurrence of atrial fibrillation after cardioversion.
Atrial fibrillation is a heart condition which can sometimes be successfully treated by a cardioversion.
Cardioversion involves resetting the heart back to normal with the use of electric current.
There is a tendency for the atrial fibrillation to recur , days weeks or even months after the cardioversion.
Fish oil supplements may be of benefit to patients with heart problems Recent evidence suggests that fish oils may be beneficial to patients with rhythm disturbances.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- Patients with persistent Atrial Fibrillation on Warfarin.
Exclusion Criteria
- paroxysmal atrial fibrillation with self terminating episodes.
- left atrial size>6.0cm
- myocardial infarction in the previous 6 months.
- contraindications to amiodarone use .
- cardiac surgery in the previous 3 months .
- an acute reversible illness contributing to the development of af
- a QTc interval > 480ms.
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Fish oil Fish oil Patients given 6g/day of fish oil containing 1.8g/d of EPA+DHA in a 1.5:1 ratio.
- Primary Outcome Measures
Name Time Method Recurrence of atrial fibrillation followed cardioversion 1 year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Royal Melbourne hospital
🇦🇺Melbourne, Victoria, Australia