Randomized phase II study of clinical effect of ghrelin administration for DCF with esophageal cancer patients - Randomized phase II study of clinical effect of ghrelin administration for DCF with esophageal cancer patients

Osaka University School of Medicine Gastroenterological Surgery0 个研究点目标入组 40 人开始时间: 2015年7月2日最近更新: 2023年10月17日

试验速览

阶段: 2 期
状态: 已完成
发起方
入组人数: 40

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

Blood acyl ghrelin, total ghrelin, and IGF-1 concentrations on day 4 were significantly higher in the ghrelin group. The renal dysfunction, serum creatinine and cystatin C levels, dose reduction, and delay in the initiation of the second cycle of chemotherapy were lower in the ghrelin group than in the control group. Serum creatinine levels were significantly correlated with serum IGF-1 levels.

研究设计

研究类型: Interventional

入排标准

年龄范围: 20years-old 至 80years-old（—）
性别: All

入选标准

未提供

排除标准

•1. Patients with severe co morbid conditions 2. other active malignancy 3. judged as inappropriate by physician-in-charge 4. combination with radiation therapy 5. lactation and pregnancy

研究者

发起方

Osaka University School of Medicine Gastroenterological Surgery

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