Taste function after chorda tympani injury

Recruiting

Conditions: loss of taste function
sensorineural hearing loss
deafness
conductive hearing loss
otosclerosis

Registration Number: NL-OMON20460

Lead Sponsor: niversity Medical Center Utrecht

Brief Summary: ot applicable

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 154

Inclusion Criteria

•Signed Informed Consent form
•Age = 18 years
•Scheduled or on the waiting list of primary stapes surgery or primary cochlear implantation
•Willingness and ability to participate in all scheduled procedures outlined in the study protocol
•Good understanding of the Dutch language

Exclusion Criteria

•Previous middle ear surgery (with the exception of the placement of ventilation tubes in childhood)
•Disability that could interfere with taste evaluation and/or questionnaire fulfilment
•History of chemotherapy and/or radiotherapy
•History of facial nerve palsy
•Cardiac pacemaker
•Pregnancy
•History of orofacial pain
•History of dysesthesia in the orofacial region
•Local evidence of a pathological condition of the oral mucosa

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the prognostic effect of CTN injury on postoperative taste function measured using taste strips in patients undergoing primary stapes surgery or primary cochlear implantation.

Secondary Outcome Measures

Name	Time	Method
•To compare the postoperative EGM threshold in uA for different locations of the tongue in patients between two types of CTN injury (stretching or sacrificing)<br>•To compare the presence of postoperative symptoms of taste disturbance in patients between two types of CTN injury (stretching or sacrificing).<br>•To compare the postoperative perception of appetite, hunger and sensory in patients between two types of CTN injury (stretching or sacrificing).<br>•To compare the postoperative quality of life in patients between two types of CTN injury (stretching or sacrificing).<br>•To compare the postoperative enjoyment of food in patients between two types of CTN injury (stretching or sacrificing).<br>•To compare the postoperative food preference in patients between two types of CTN injury (stretching or sacrificing).<br>•To compare the postoperative odour identification score in patients between two types of CTN injury (stretching or sacrificing)