Benefits of ICD in patients with valvular cardiomyopathy

Not Applicable

Active, not recruiting

Conditions: Diseases of the circulatory system

Registration Number: KCT0004228

Lead Sponsor: Keimyung University Dongsan Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Active, not recruiting

Sex: All

Target Recruitment: 122

Inclusion Criteria

•Adults 19 to 75 years
•Patients who meet one of the following criteria:
?Patients who have undergone surgery for aortic valve or mitral valve disease for more than 12 months
?Patients with severe aortic valve or mitral valve disease
•Patients with left ventricular ejection fraction = 35% by echocardiography or other imaging methods
•US, European practice guidelines class I indication for ICD implantation
•Patients without evidence of ischemic heart disease (who meet one of the following criteria):
?Stress test negative
?Significant stenosis was not observed in coronary artery images:epicardial coronary stenosis <70%, left main stenosis <50%
•History of heart failure symptoms
•Patients who have received medication for more than 3 months according to the heart failure treatment guideline recommendation

Exclusion Criteria

•Patients with left ventricular dysfunction without valvular heart disease
•Patients who require cardiac pacing therapy due to bradycardia
•Heart transplant scheduled
•Life expectancy is less than one year

Study & Design

Study Type: Observational Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ICD therapy that effectively terminate life-threatening arrhythmia: anti-tachycardia pacing, shock therapy

Secondary Outcome Measures

Name	Time	Method
mortality was recorded and it will be classified into cardiogenic/non-cardiogenic death. Especially, arrhythmic death was recorded separately.;Inappropriately delivered ICD therapy (eg. ICD therapy delivered during sinus tachycardia);Analyze the type of ventricular arrhythmia