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LLLT for Alopecia of the Eyebrow in Women

Not Applicable
Completed
Conditions
Alopecia
Interventions
Device: LLLT
Registration Number
NCT04897555
Lead Sponsor
Freedom Laser Therapy, Inc.
Brief Summary

The purpose of this research is to study the ongoing effectiveness of a light therapy device for human hair growth. This device, called the iRestore Eyebrow Device, is a type of cold, or non-heat producing light therapy system that will emit light on the hair growth cells within and around the hair follicle. When these cells do not function properly, one may experience common problems such as baldness and thinning or brittle hair. The application of a special category of low-level light to be studied in the project may cause an increase in essential nutrients to the damaged hair follicles and skin cells, leading to a reduction in hair loss and in some cases, possibly leading to re-growth.

Detailed Description

This study on LLLT aims to define the safety and physiologic effects that occur when the human hair follicle and surrounding tissue structures are exposed to this type of radiation. Thus far, all reports on the efficacy of laser light and LED light in this area, have been, in large part, unsupported by multi-center, randomized, double blind, controlled studies. To properly identify the effects in human subjects, exposure to LLLT is not sufficient. The analysis of the non-radiated and radiated tissues is required to elucidate the tissue response and efficacy of the laser therapy. The theory that is widely accepted is that the mitochondria are the powerhouse of the stem cells that cause hair growth. The LLLT "turns on" the nutrient pump process that energizes the mitochondria, which leads to an increase in ATP and subsequent reversal of hair follicles from the dormant stage of growth called telogen, to the active growth stage called anagen.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
40
Inclusion Criteria
  • Female subjects experiencing any type of non-traumatic eyebrow hair loss.
  • Apparent good health.
Exclusion Criteria
  • Previous involvement in other eyebrow hair studies.
  • Use of any hair growth agent within the last 4 weeks.
  • Evidence of any current viral, fungal or bacterial infection.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
LLLT Active TreatmentLLLTLLLT Therapy will be administered to the treatment site.
Primary Outcome Measures
NameTimeMethod
Change in number of terminal hairs12 weeks

Pre \& Post treatment terminal hair counts

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

NST Consultants, Inc.

🇺🇸

Mendham, New Jersey, United States

Bodian Dermatology

🇺🇸

Great Neck, New York, United States

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